הצגת מקרה 5 - התשובה

Tal Arazi-Kleinman M.D.
Diagnostic Imaging Department, Shiba Medical Center, Tel Hashomer, Affiliated to Sackler Medical School, Tel Aviv University, Ramat Aviv

C. Pancreatic neuroendocrine tumour (Islet cell tumour)

• The main differential diagnosis of a large solid mass at the tail of the pancreas isodense to normal pancreatic parenchyma with calcifications that enhances post contrast injection is non functional neuroendocrine tumor. Most pancreatic adenocarcinomas are hypoenhancing with respect to the surrounding normal parenchyma on dynamic contrast enhanced CT. Functional neuroendocrine tumors demonstrate very small hypervascular lesions on dynamic contrast enhanced CT.
  

Further reading:

Kalra MD, Maher MM, Mueller PR and Saini S. State of the art imaging of pancreatic neoplasms. Br J Radiol 2003; 76: 857-865.